Prescott celebrates biggest NFL payday with victory

Dak Prescott has barely had time to celebrate getting the biggest contract in NFL history before learning it came with a price.

His Dallas teammates all want something.

"They're expecting Rolexes," Prescott joked.

"Everybody's giving me their wrist size."

Prescott threw a touchdown pass hours after agreeing to a four-year, $US240 million ($A359 million) contract, with the Cowboys throttling the Browns 33-17 in their season opener in Cleveland on Sunday.

Prescott's deal makes him the first player to average $US60 million ($A90 million) per season and ends months of speculation about his future with Dallas, who have won 12 games in each of the past three years with him.

Earlier this week, Prescott, who was coming off his best season and entering his final year under contract, said he wants to be the quarterback to finally end the team's Super Bowl drought. He'll have time to try.

"It's about holding up my end of the deal," said Prescott, who completed 19 of 32 passes for 179 yards and spent much of the second half relaxing on the sideline.

Prescott threw a 21-yard scoring pass to Brandin Cooks in the first quarter and the Cowboys opened a 27-3 lead early in the third on KaVontae Turpin's 60-yard punt return TD.

Brandon Aubrey kicked field goals of 57, 50, 46 and 40 yards for Dallas.

Prescott's deal came just two weeks after Dallas gave wide receiver CeeDee Lamb a four-year, $US136 million ($A203 million) contract. Lamb sat out all of training camp before the sides reached an agreement.

Caleb Williams had a rough debut for Chicago but got bailed out by his defence, with Tyrique Stevenson returning an interception 43 yards for the go-ahead touchdown to give the Bears a 24-17 victory over Tennessee.

Williams, the No.1 overall pick, finished 14 of 29 for 93 yards. The former Heisman Trophy winner still became the first quarterback drafted first overall to win his debut start since 2002.

With Russell Wilson's Pittsburgh debut put on hold by a calf injury, Justin Fields stepped in to lead the Steelers to a 18-10 victory over the Falcons in Atlanta.

Chris Boswell booted six field goals, three of them longer than 50 yards, and the Steelers made life miserable for Kirk Cousins in his first game as Atlanta's big-money quarterback.

Elsewhere, there were home wins for Detroit, after overtime, Buffalo, Miami, New Orleans, Seattle and Tampa Bay, while New England, Houston, Minnesota and the Los Angeles Chargers triumphed on their travels.